Unprovoked Extensive Cerebral Venous Sinus Thrombosis in a Heterozygous Prothrombin G20210A Mutation Carrier: A Rare Case Report

Authors

Hasan Obeidat, Department of Internal Medicine, MedStar Health – Union Memorial Hospital, Baltimore, MD, USAFollow
Sandeep Kshetri, Department of Internal Medicine, Manipal College Of Medical Sciences, Pokhara, Nepal
Mahyar Toofantabrizi, Department of Internal Medicine, MedStar Health – Franklin Square Medical Center, Baltimore, MD, USA

Abstract

Cerebral Venous Sinus Thrombosis (CVST) is a rare condition accounting for approximately 1% of all strokes. It can occur secondary to various causes, including inherited thrombophilia, with Prothrombin G20210A mutation being the second most common. Extensive unprovoked CVST in heterozygous carriers is uncommon. This case underscores the importance of evaluating inherited thrombophilia in unprovoked CVST. Long-term, multidisciplinary follow-up is vital for managing post-thrombotic sequelae.

Recommended Citation

Obeidat, Hasan; Kshetri, Sandeep; and Toofantabrizi, Mahyar (2026) "Unprovoked Extensive Cerebral Venous Sinus Thrombosis in a Heterozygous Prothrombin G20210A Mutation Carrier: A Rare Case Report," Journal of Community Hospital Internal Medicine Perspectives: Vol. 16: Iss. 2, Article 14.
DOI: 10.55729/2000-9666.1584
Available at: https://scholarlycommons.gbmc.org/jchimp/vol16/iss2/14

DOI

10.55729/2000-9666.1584