UTILIZATION OF ANTIVIRAL TREATMENT FOR HOSPITALIZED PATIENTS WITH MILD-TO-MODERATE COVID-19 AT HIGH RISK FOR DISEASE PROGRESSION

Authors

Michael P. Iannetti, Internal Medicine Physician Charleston Area Medical Center, 1220 Lee Street East, Suite 110 Charleston, WV 25301Follow
Katie Barnes, Medical Student West Virginia University, Charleston Division 3200 MacCorkle Ave SE Charleston, WV 25304
Stephen Varga, Resident Physician Wayne State University SJMO Medical Office Building Pontiac, MI 48341
Suzanne Kemper, Sr. Research Associate Charleston Area Medical Center Institute for Academic Research 3110 MacCorkle Ave, SE Charleston, WV 25304
Elaine Davis Mattox, Director, Health Services and Outcomes Research Charleston Area Medical Center Institute for Academic Research 3110 MacCorkle Ave, SE Charleston, WV 25304

Abstract

Clinicians frequently encounter patients in the hospital with mild-to-moderate COVID-19 who are at high risk for disease progression. Antiviral drugs reduce the rate of progression to severe COVID-19 when given to these patients within 5-7 days of symptom onset. To look at the utilization of antiviral medications in hospitalized patients with mild-to-moderate COVID-19, a detailed chart review was conducted of 500 randomly selected patients from the Charleston Area Medical Center COVID-19 Registry. We identified 124 patients with mild-to-moderate COVID-19 who were eligible for antiviral treatment. Only 41 of the 124 patients (33.1%) received antiviral treatment. Providers listed mild symptoms as the most common reason (74.7%) that antiviral treatment was not started. These findings show that antiviral medications are underutilized in treating high-risk hospitalized patients with mild-to-moderate COVID-19 to prevent disease progression.

Recommended Citation

Iannetti, Michael P.; Barnes, Katie; Varga, Stephen; Kemper, Suzanne; and Mattox, Elaine Davis (2025) "UTILIZATION OF ANTIVIRAL TREATMENT FOR HOSPITALIZED PATIENTS WITH MILD-TO-MODERATE COVID-19 AT HIGH RISK FOR DISEASE PROGRESSION," Journal of Community Hospital Internal Medicine Perspectives: Vol. 15: Iss. 6, Article 5.
DOI: 10.55729/2000-9666.1552
Available at: https://scholarlycommons.gbmc.org/jchimp/vol15/iss6/5

DOI

10.55729/2000-9666.1552