A Rare, Cephalosporin-Induced Rash: Acute Generalized Exanthematous Pustulosis

Authors

Mark A. Colantonio, Department of Medicine, West Virginia University, Morgantown, West Virginia, USAFollow
Danielle Sblendorio, Department of Neurology, West Virginia University, Morgantown, West Virginia, USA
Elizabeth Hart, Department of Medicine, West Virginia University, Morgantown, West Virginia, USA
Vincent Melemai, West Virginia University School of Medicine, 1 Medical Center Dr. Morgantown, WV 26506
Joshua Wiley, Department of Medicine, West Virginia University, Morgantown, West Virginia, USA

Abstract

Acute generalized exanthematous pustulosis is an uncommon cause of rash, typically presenting with pustules with an erythematous base and associated skin-peeling. Frequently caused by medications, including penicillins and quinolones, cephalosporins are rarely reported as an offending agent. Here, we present a case of rare acute generalized exanthematous pustulosis secondary to recent cephalosporin use presenting to our rural healthcare facility. We aim to raise awareness of this unusual rash secondary to cephalosporin use.

Recommended Citation

Colantonio, Mark A.; Sblendorio, Danielle; Hart, Elizabeth; Melemai, Vincent; and Wiley, Joshua (2025) "A Rare, Cephalosporin-Induced Rash: Acute Generalized Exanthematous Pustulosis," Journal of Community Hospital Internal Medicine Perspectives: Vol. 15: Iss. 4, Article 24.
DOI: 10.55729/2000-9666.1512
Available at: https://scholarlycommons.gbmc.org/jchimp/vol15/iss4/24