Abstract
Autoimmune lupus enteritis in systemic lupus erythematosus (SLE) is a rare manifestation that comprises of gastrointestinal tract inflammation with supportive images and/or biopsy findings. We report a unique case of widespread lupus enteritis occurring late in the disease process and in isolation without additional features of active SLE but in the presence of SLE serological activity. There was no clear evidence of active mesenteric vasculitis, intestinal pseudo-obstruction, protein-losing enteropathy, or coagulopathy by imaging or histopathology. This is the first reported case of an SLE patient with pan-gastrointestinal involvement of lupus enteritis responding to Belimumab, with complete resolution of the gastrointestinal syndrome and no further recurrence of gastrointestinal events. Rapid diagnosis and prompt immunomodulatory treatment of lupus-related enteritis are critical to avoid potentially life-threatening complications.
Recommended Citation
Shaik, Mohammed Rifat; Shaikh, Nishat Anjum; Huang, Yuting; Pandey, Ankur; Wheeler, Erika; and Mikdashi, Jamal
(2023)
"Autoimmune Lupus Enteritis with Pan Gastrointestinal Involvement in an Adult Patient with Systemic Lupus Erythematosus: Complete Response to Belimumab,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 13:
Iss.
4, Article 4.
DOI: 10.55729/2000-9666.1185
Available at:
https://scholarlycommons.gbmc.org/jchimp/vol13/iss4/4
