Abstract
Most cases of Myxedema Coma are associated with primary hypothyroidism characterized by significantly elevated TSH levels. However, this case presents an atypical manifestation of myxedema coma with low TSH levels despite severe hypothyroidism. The rarity of this presentation lies in the absence of central lesions typically responsible for such TSH suppression. This highlights a critical consideration: the profound impact of severe sepsis on thyroid hormone regulation and the hypothalamus-pituitary-thyroid axis.
Recommended Citation
Hasan, Nazmul; Yang, Daniel; Othman, Thaer; and Dai-Ju, Jenny
(2024)
"Atypical Thyroid Stimulating Hormone Levels in Myxedema Coma Complicated by Severe Sepsis,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 14:
Iss.
6, Article 22.
DOI: 10.55729/2000-9666.1412
Available at:
https://scholarlycommons.gbmc.org/jchimp/vol14/iss6/22