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Ayrton Bangolo, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Pierre Fwelo, Department of Epidemiology, Human Genetics, and Environmental Sciences, UTHealth School of Public Health, Houston, Texas, USA
Amer Jarri, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Sai Priyanka Pulipaka, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Vignesh K. Nagesh, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Nikita Wadhwani, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USAFollow
Budoor Alqinai, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Sidra Sohail, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Geetha Keshav, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Angel Ann Chacko, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Aiswarya Menon, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Luis Periel, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Zuhair S. Siddiqui, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Bibek Pyakurel, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Sandra Kunnel, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Matthew Maturasingh, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Gillan Quirequire, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Jerusha Gudapati, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Ashfi Hoque, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Zubair Habib, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Varun Rao, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Jasmine K. Grewal, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Abraham Lo, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA
Simcha Weissman, Department of Internal Medicine, Hackensack Meridian Health/Palisades Medical Center, North Bergen, NJ, USA

Abstract

Background: Malignant Pleural Mesothelioma is a primary pleural tumor with scarce prognostic data estimates given its rarity. This study aims to explore the epidemiologic and survival predictors amongst patients with MPM, extending from the largest and most recent study conducted between 1973 and 2009. Methods: 3,384 patients diagnosed with MPM between 2010 and 2017 were enrolled from the SEER database. Demographics, clinical characteristics, and mortality estimates were analyzed. Multivariate Cox model was used to identify independent prognostic factors. Results: Our cohort revealed a male predominance (77.16%), with over 80% diagnosed after age 59. Epithelioid mesothelioma (41.78%), non-Hispanic whites (78.13%), and diagnosis at distant stage (71.60%) were the most common subgroups in their respective categories. 365 patients (10.79%) lacked pleural effusion at diagnosis. In multivariate analyses, higher overall mortality (OM) was associated with male gender (HR 1.24, p80 years (HR 2.17, p80 years (HR 2.02, p

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