Eosinophilic granulomatosis with polyangiitis (EGPA) also referred to as Churg-Strauss syndrome is a rare vasculitis of the small to medium vessels. We present a rare case of acute coronary artery dissection brought on by EGPA, which generally has a poor prognosis. A 41-year-old male with history of bronchial asthma presented to the emergency room with a 2-week history of dyspnea, cough with clear phlegm, and fever. For the past eight months he had experienced episodes with similar symptoms relieved by steroids. CT chest showed bilateral upper lobe patchy opacities with extensive workup for infectious etiology being negative. He had peripheral eosinophilia with sinusitis. He had acute coronary syndrome and Coronary angiogram showed Right coronary artery dissection. After making a diagnosis of EGPA based on American college of Rheumatology criteria, he was successfully treated with high dose immunosuppression. Coronary artery dissection is a fatal and uncommon complication of EGPA which is usually diagnosed postmortem. Early recognition of this condition ante mortem and aggressive treatment can be lifesaving as demonstrated in our case.
Vivek, Vidhyalakshmy; Yadav, Sumeet; Korsapati, Hariprasad Reddy; Mir, Mikael; Jain, Shika; Jama, Abbas B.; Trivedi, Setu; Xu, Qiping; Meda, Namratha Seetharam; Ali, Syed; Khedr, Anwar; Hassan, Esraa; Attallah, Noura; Patnaik, Harsha; Obulareddy, Sri Usha Jeevani; Rauf, Ibtisam; Korsapati, Aishwarya Reddy; Surani, Salim; Khan, Syed Anjum; Jain, Nitesh Kumar; and Bawaadam, Hasnain
"Coronary artery dissection and Myocarditis caused by Eosinophilic granulomatosis with polyangiitis (EGPA): A case report,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 13:
5, Article 10.
Available at: https://scholarlycommons.gbmc.org/jchimp/vol13/iss5/10