Reversible Cerebral Vasoconstriction Syndrome Associated with Oxybutynin Use; a Brief Review of Pathophysiology

Authors

Wahab J Khan, The University of South Dakota Sanford School of medicine, Sioux Falls, SD USAFollow
Muhammad Asif, The University of South Dakota Sanford School of medicine, Sioux Falls, SD USA
Sadia Aslam, Avera McKennan Hospital and University Health Center, Sioux Falls, SD USA
Ifrah Nadeem, The University of South Dakota Sanford School of medicine, Sioux Falls, SD USA
William Rossing, The University of South Dakota Sanford School of medicine, Sioux Falls, SD USA

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by reversible vasospasm of the central nervous system vasculature. It usually presents as a classic thunderclap headache, but complications like a stroke, seizure, or intracranial hemorrhage may occur at the onset. Most cases are linked temporally to secondary agents. The most common suggested mechanism underlying the RCVS is vascular tone dysregulation. Our report describes the RCVS incidence associated with oxybutynin use in a young female. We aim to describe the potential pathophysiology linking oxybutynin use and RCVS.

Recommended Citation

Khan, Wahab J; Asif, Muhammad; Aslam, Sadia; Nadeem, Ifrah; and Rossing, William (2023) "Reversible Cerebral Vasoconstriction Syndrome Associated with Oxybutynin Use; a Brief Review of Pathophysiology," Journal of Community Hospital Internal Medicine Perspectives: Vol. 13: Iss. 4, Article 7.
DOI: 10.55729/2000-9666.1192
Available at: https://scholarlycommons.gbmc.org/jchimp/vol13/iss4/7