Abstract
Hepatocellular carcinoma (HCC) is considered the leading cause of primary liver malignancy, however, a tumor arising from the biliary tree should be always kept among the differential diagnosis. Cholangiocarcinoma (CCA) is a group of primary liver malignancies that represents 10-20% of all primary liver masses being perihilar cholangiocarcinoma the most common and intrahepatic the less common subtype. Important biomarkers such as serum alpha-fetoprotein (AFP) are commonly measured. An elevated AFP > 400 ng/mL is very specific for HCC. On the contrary, AFP levels rarely exceed 20 ng/mL in patients with intrahepatic cholangiocarcinoma. We report a case of a patient with a markedly elevated serum AFP who was found to have ICC.
Recommended Citation
Romero, Ana L.; Romero, Jesus; Lee, Janice; Iqbal, Unzela; Masood, Abdullah; Koomson, Angela; and Muniba, Naqi
(2023)
"Intrahepatic Cholangiocarcinoma in a Patient with Alcoholic Liver Cirrhosis and Markedly Elevated Serum Alpha-Fetoprotein,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 13:
Iss.
4, Article 11.
DOI: 10.55729/2000-9666.1204
Available at:
https://scholarlycommons.gbmc.org/jchimp/vol13/iss4/11
