Amyloid is a systemic disease characterized by extracellular deposition of misfolded protein. Gastrointestinal and peritoneal deposition of light chain (AL) amyloid is an under-recognized manifestation of this systemic disease, usually as a late sequela. Here we present a case of recently diagnosed AL peritoneal amyloid that presented in the context of recurrent, acute onset abdominal discomfort and was found to have bowel obstruction complicated by perforation in the setting of AL-mediated gastrointestinal tract infiltration and dysmotility.
Acharya, Indira; Dominah, Gifty A.; Xing, Dongmei; Allen, Elizabeth; Iding, Jeffrey S.; and Haas, Christopher J.
"Peritoneal Amyloidosis as a Presenting Manifestation of AL Amyloid,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 13:
3, Article 19.
Available at: https://scholarlycommons.gbmc.org/jchimp/vol13/iss3/19