Classic IgA-Vasculitis with Nephrotic Range Proteinuria - Rare Presentation in an Adult

Authors

Ella Teplitsky, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Maryam Zafar, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Abubakar Tauseef, Resident Physician in Internal Medicine Department Creighton University School of MedicineFollow
Marissa Varghese, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Joseph Thirumalareddy, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Sunil Nair, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Akshat Sood, Resident Physician in Internal Medicine Department Creighton University School of Medicine
Mohsin Mirza, Resident Physician in Internal Medicine Department Creighton University School of Medicine

Abstract

IgA vasculitis formerly known as Henoch-Schonlein Purpura is characterized by leukocytoclastic vasculitis and IgA immune complex in small vessels of the affected organ. IgA vasculitis can involve any organ system depending upon the deposition of the IgA immune complex. IgA vasculitis is a clinical diagnosis which manifest with abdominal pain, arthralgia/arthritis, palpable purpura, and kidney involvement. Occasionally, serum IgA levels or skin or kidney biopsy can help in confirming the diagnosis. Treatment is usually supportive, but studies have proved that prednisone or immunosuppressive agents can help in the prevention or progression of the disease. Hereby we present a case of 54-year-old Caucasian male who developed classic tetrad findings of IgA vasculitis most likely after receiving monkeypox vaccine which patient received three weeks prior to presentation to the hospital. Kidney involvement was present but surprisingly proteinuria was above nephrotic range making it as a rare presentation of IgA vasculitis.

Recommended Citation

Teplitsky, Ella; Zafar, Maryam; Tauseef, Abubakar; Varghese, Marissa; Thirumalareddy, Joseph; Nair, Sunil; Sood, Akshat; and Mirza, Mohsin (2023) "Classic IgA-Vasculitis with Nephrotic Range Proteinuria - Rare Presentation in an Adult," Journal of Community Hospital Internal Medicine Perspectives: Vol. 13: Iss. 3, Article 13.
DOI: 10.55729/2000-9666.1171
Available at: https://scholarlycommons.gbmc.org/jchimp/vol13/iss3/13