Cardiac amyloidosis is caused by abnormal deposit of amyloid in the myocardium and can be divided into light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis. ATTR amyloidosis can be further divided into wild-type and mutant type based on genetic mutation. Differentiation between AL, wild-type, and mutant type ATTR amyloidosis has significant prognostic and therapeutic implications.
Qian, Xiaoxiao; Bakhshi, Hooman; Biswas, Rakesh; Gattani, Raghav; and Kennedy, Jamie L
"Concurrent Waldenstrom Macroglobulinemia and Mutant Transthyretin Cardiac Amyloidosis,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 12:
6, Article 15.
Available at: https://scholarlycommons.gbmc.org/jchimp/vol12/iss6/15