Squamous cell carcinoma (SCC) of the rectum is a rare malignancy, and the optimal treatment strategy remains unknown. Cases are limited in the literature, and although historically treated with surgical resection, more recent cases have suggested success with chemotherapy. Although Nigro protocol was initially developed for anal SCC, we present a case of rectal SCC successfully treated with the Nigro protocol. Our case supports the use of chemoradiotherapy as initial treatment for rectal SCC over surgery.
Chaudhry, Hunza; Sandhu, Sunny; Tasso, David; and Prajapati, Devang
"A Rare Case of Rectal Squamous Cell Carcinoma Treated with Nigro Protocol,"
Journal of Community Hospital Internal Medicine Perspectives: Vol. 12:
5, Article 18.
Available at: https://scholarlycommons.gbmc.org/jchimp/vol12/iss5/18