A Fatal Etiology of Splenic Infarction

Authors

David Masterman, Division of Hospital Medicine, Johns Hopkins Bayview Medical Center BaltimoreFollow
Amteshwar Singh, Division of Hospital Medicine, Johns Hopkins Bayview Medical Center Baltimore
Tanmay Singh, Department of Radiation Oncology, Johns Hopkins University School of Medicine
Ashampreet Kaur, Department of Medicine, Sri Guru Ram Das Institute of Medical Sciences & Research
Sonal Gandhi, Division of Hospital Medicine, Johns Hopkins Bayview Medical Center Baltimore

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary conditions with a wide range of underlying etiologies. When either condition is identified, a prompt search for the underlying trigger is needed to prevent devastating consequences. We demonstrate the difficulties and barriers that can delay the diagnosis of HLH, and emphasize the importance of early treatment in improving survival rates.

Recommended Citation

Masterman, David; Singh, Amteshwar; Singh, Tanmay; Kaur, Ashampreet; and Gandhi, Sonal (2022) "A Fatal Etiology of Splenic Infarction," Journal of Community Hospital Internal Medicine Perspectives: Vol. 12: Iss. 5, Article 15.
DOI: 10.55729/2000-9666.1097
Available at: https://scholarlycommons.gbmc.org/jchimp/vol12/iss5/15