Title
Hepatitis D virus and liver transplantation: Indications and outcomes
Document Type
Article
Publication Title
World Journal of Hepatology
Abstract
Hepatitis D virus (HDV) is a dependent virus that relies on hepatitis B virus for its replication and transmission. Chronic hepatitis D is a severe form of viral hepatitis that can result in end stage liver disease. Currently, pegylated interferon alpha is the only approved therapy for chronic HDV infection and is associated with significant side effects. Liver transplantation (LT) is the only treatment option for patients with end-stage liver disease, hepatocellular carcinoma, or fulminant hepatitis due to coinfection with HDV. As LT for HDV and hepatitis B virus coinfection is uncommon in the United States, most data on the long-term impact of LT on HDV are from international centers. In this review, we discuss the indications and results of LT with treatment options in HDV patients.
First Page
291
Last Page
299
DOI
https://doi.org/10.4254/wjh.v13.i3.291
Publication Date
Spring 3-27-2021
Recommended Citation
Muhammad H, Tehreem A, Hammami MB, Ting PS, Idilman R, Gurakar A. Hepatitis D virus and liver transplantation: Indications and outcomes. World J Hepatol. 2021 Mar 27;13(3):291-299. doi: 10.4254/wjh.v13.i3.291. PMID: 33815673; PMCID: PMC8006082.